021-51111890
购物车（）
sales@molnova.cn
Daclatasvir dihydrochloride
CAS No. 1009119-65-6
Daclatasvir dihydrochloride ( BMS-790052 dihydrochloride;BMS790052 dihydrochloride;BMS 790052 dihydrochloride )
产品货号. M10060 CAS No. 1009119-65-6
A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥284 | 有现货 |
|
| 10MG | ￥348 | 有现货 |
|
| 25MG | ￥446 | 有现货 |
|
| 50MG | ￥527 | 有现货 |
|
| 100MG | ￥599 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Daclatasvir dihydrochloride
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons.
-
产品描述A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons; exhibits picomolar EC(50) towards replicons expressing a broad range of HCV genotypes and the JFH-1 genotype 2a infectious virus in cell culture.HCV Infection Approved
-
同义词BMS-790052 dihydrochloride;BMS790052 dihydrochloride;BMS 790052 dihydrochloride
-
通路Microbiology/Virology
-
靶点HCV
-
受体HCVNS5A
-
研究领域Infection
-
适应症HCV Infection
化学信息
-
CAS Number1009119-65-6
-
分子量811.80
-
分子式C40H52Cl2N8O6
-
纯度>98% (HPLC)
-
溶解度DMSO: ≥ 56 mg/mL
-
SMILESCC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C(N5)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC.Cl.Cl
-
化学全称Carbamic acid, N,N'-[[1,1'-biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester, hydrochloride (1:2)
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Gao M, et al. Nature. 2010 May 6;465(7294):96-100.
2. Lemm JA, et al. Antimicrob Agents Chemother. 2011 Aug;55(8):3795-802.
3. Fridell RA, et al. Antimicrob Agents Chemother. 2010 Sep;54(9):3641-50.
4. Fridell RA, et al. J Virol. 2011 Jul;85(14):7312-20.
2. Lemm JA, et al. Antimicrob Agents Chemother. 2011 Aug;55(8):3795-802.
3. Fridell RA, et al. Antimicrob Agents Chemother. 2010 Sep;54(9):3641-50.
4. Fridell RA, et al. J Virol. 2011 Jul;85(14):7312-20.
产品手册
关联产品
-
R-7128
The prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.
-
Boceprevir
A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
-
VCH-916
VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.
